Parkinson’s, which is extra widespread in males than girls, normally begins about age 60 as nerve cells within the mind (neurons) develop into weak or broken. Signs could embody trembling or shaking (tremor), muscle stiffness (rigidity), gradual motion (bradykinesia) and poor stability and coordination. As signs worsen, individuals could have hassle strolling, speaking or persevering with to do routine every day actions.